Publications

Main publications of Marat Yusupov and Gulnara Yusupova on eukaryotic ribosome structural studies
Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome Pellegrino S, Meyer M, Könst ZA, Holm M, Voora VK, Kashinskaya D, Zanette C, Mobley DL, Yusupova G, Vanderwal CD, Blanchard SC, Yusupov M Nucleic Acids Research (2019) 47: 3223-3232
Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance Pellegrino S, Demeshkina N, Mancera-Martinez E, Melnikov S, Simonetti A, Myasnikov A, Yusupov M, Yusupova G, Hashem Y J Mol Biol (2018) 430: 2677-2687

The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth Pellegrino S, Meyer M, Zorbas C, Bouchta SA, Saraf K, Pelly SC, Yusupova G, Evidente A, Mathieu V, Kornienko A, Lafontaine DLJ, Yusupov M
Structure (2018) 26: 416-425

Aminoglycoside interactions and impacts on the eukaryotic ribosome Prokhorova I, Altman RB, Djumagulov M, Shrestha JP, Urzhumtsev A, Ferguson A, Chang CT, Yusupov M, Blanchard SC, Yusupova G Proceedings of the National Academy of Sciences of the United States of America (2017) 114: E10899-E10908

Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides Könst ZA, Szklarski AR, Pellegrino S, Michalak SE, Meyer M, Zanette C, Cencic R, Nam S, Voora VK, Horne DA, Pelletier J, Mobley DL, Yusupova G, Yusupov M, Vanderwal CD
Nature Chemistry (2017) 9: 1140-1149

Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A McClary B, Zinshteyn B, Meyer M, Jouanneau M, Pellegrino S, Yusupova G, Schuller A, Reyes JCP, Lu J, Guo Z, Ayinde S, Luo C, Dang Y, Romo D, Yusupov M, Green R, Liu JO Cell Chemical Biology (2017) 24: 605-613

Crystal structure of eukaryotic ribosome and its complexes with inhibitors Yusupova G, Yusupov M.
Philos Trans R Soc Lond B Biol Sci (2017) 372: 20160184

Molecular insights into protein synthesis with proline residues
Melnikov S, Mailliot J, Rigger L, Neuner S, Shin BS, Yusupova G, Dever TE, Micura R, Yusupov M
EMBO Rep (2016) 17: 1776-1784

Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome
Prokhorova IV, Akulich KA, Makeeva DS, Osterman IA, Skvortsov DA, Sergiev PV, Dontsova OA, Yusupova G, Yusupov MM, Dmitriev SE
Science Reports (2016) 6: 27720

Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome
Melnikov S, Mailliot J, Shin BS, Rigger L, Yusupova G, Micura R, Dever TE, Yusupov M
J Mol Biol (2016) 428: 3570-3576

Structural basis for the inhibition of the eukaryotic ribosome
Garreau de Loubresse N, Prokhorova I, Holtkamp W, Rodnina MV, Yusupova G, Yusupov M
Nature (2014) 513: 517-522

High-resolution structure of the eukaryotic 80S ribosome
Yusupova G, Yusupov M
Annu Rev Biochem (2014) 83: 467-486

The complete structure of the eukaryotic ribosome at 3Å resolution
Ben-Shem A, Garreau De Loubresse N, Melnikov S, Jenner L, Yusupova G, Yusupov M
Science (2011) 334: 1524-1529

Crystal structure of the eukaryotic ribosome
Ben-Shem A, Jenner L, Yusupova G, Yusupov M
Science (2010) 330: 1203-1209